OUR MISSION
The Faure lab is located at Texas Woman's University. Our mission is to characterize new genes to understand better how lipids are made and regulated or their functions for different cellular processes. Our lab mainly focuses on studying lipid droplet production in A. thaliana.
OUR RESEARCH FOCUS
1- Our primary research is to develop new genetic strategies to engineer new crops producing sustainable amounts of biomass for biodiesel production. Our journey led us to use unusual genes to redirect the carbon flux for plant lipid synthesis.
Finding novel genetic strategies to improve lipid synthesis and LD assembly in plant cells will provide a sustainable approach to producing the biomass needed for our biofuel needs. The best approach is to redirect the flux of carbon from different directions (i.e., synthesis, catabolism, packaging) into LD production. Using the plant model Arabidopsis thaliana and innovative genes, we are trying to select the best candidates to increase the level of lipids in plant cells significantly.
2- We also collaborate with the Gumienny lab to study the impact of the TGF-beta pathway on the synthesis of the lipid barrier present in the worm's cuticle. This lipid barrier protects worms against the dangers of their environment (e.g., chemicals, pathogens, etc.)
3- In collaboration with Dr. Spencer (TWU), we helped investigate the impact of human viruses on the lipid content of hematopoietic cells.
4- In collaboration with Dr. Salazar (Chemistry, TWU) we helped to study the impact of different microplastics and chemical on plants development.Â
The main techniques used in our lab include but are not limited to the following:
Molecular techniques: DNA/RNA/Protein extraction, PCR, RT-PCR, Western blot, etc.
RNA sequencing and quantitative PCR
Biochemistry: lipid extraction, SPE, TCL, GC-MS
Microscopy: confocal, epifluorescence
Plant transformation (stable or transient) using bacteria-mediated delivery
